Provocative article on school closures – worth a read. 
Suppose, as a thought experiment, that a company named Anredom had developed a different “vaccine” by April 2020. The difference is that theirs doesn’t work, it’s just some chemical that likely has has little effect on Covid-19. Suppose moreover that the chemical can cause brain damage when injected into humans. For many, the damage is minor and and short-lived. Others experience more serious damage and require medical intervention, but they ultimately recover within a few months or a year. But for a few—say, 1%—the damage is permanent and substantial: it renders them less able to navigate life and so lowers their life-time earnings, life-expectancy, health indicators, and other quality-of-life measures. Suppose, finally, that in April 2020 we knew enough about the chemical to predict all this, both its inefficacy against Covid-19 and its harmful effects. Nonetheless, Anredom requests that we skip clinical trials and start injecting the chemical into school-aged children right away. Should we? Of course not. The idea is sickening. I claim that extended school closures are the same in all morally relevant respects.
— Read on link.springer.com/article/10.1007/s40592-022-00161-9